SCHEMBL10431982

SCHEMBL10431982

CO[C@H]1C[C@@H](n2cc(C)c(=O)[nH]c2=O)O[C@@H]1CO

nearest known ligand 0.72

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.69
TK1 P04183 6/20 0.65
LMNA P02545 2/20 0.63
TSHR P16473 2/20 0.63
ALB P02768 1/20 0.63
PKM P14618 1/20 0.63
BLM P54132 1/20 0.63
PMP22 Q01453 1/20 0.63
CYP2D6 P10635 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL523267 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL523268 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL16359947 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL19132672 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL12670320 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL25756080 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL8996152 0.91 RNASE1 (0.70) RNASE1TK1LMNATSHRALB
SCHEMBL22992460 0.91 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL4286458 0.91 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL27989242 0.91 RNASE1 (0.69) RNASE1TK1LMNATSHRALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0391411-A2 3'-Substituted methyl nucleosides as antiviral agents Bristol-Myers Squibb Company (US) 1990-10-10 EP claimed
EP-0391411-A2 3'-Substituted methyl nucleosides as antiviral agents Bristol-Myers Squibb Company (US) 1990-10-10 EP disclosed