SCHEMBL12670320

SCHEMBL12670320

CO[C@H]1C[C@@H](n2cc(C)c(=O)[nH]c2=O)O[C@H]1CO

nearest known ligand 0.72

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ RNASE1 P07998 1/20 0.69
▸ TK1 P04183 6/20 0.65
▸ LMNA P02545 2/20 0.63
▸ TSHR P16473 2/20 0.63
▸ ALB P02768 1/20 0.63
▸ PKM P14618 1/20 0.63
▸ BLM P54132 1/20 0.63
▸ PMP22 Q01453 1/20 0.63
▸ CYP2D6 P10635 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19132672 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL523268 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL16359947 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL25756080 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL523267 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL10431982 1.00 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL8996152 0.91 RNASE1 (0.70) RNASE1TK1LMNATSHRALB
SCHEMBL22992460 0.91 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL4286458 0.91 RNASE1 (0.69) RNASE1TK1LMNATSHRALB
SCHEMBL2056647 0.91 RNASE1 (0.69) RNASE1TK1LMNATSHRALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026421-A1 METHODS FOR CAPTURING LONG POLYNUCLEOTIDES FOR SEQUENCING SPECIFIC GENOMIC REGIONS GENERATION BIOTECH, LLC (US) 2024-01-25 — — US disclosed
US-11821023-B2 Method for capturing long polynucleotides for sequencing specific gnomic regions GENERATION BIOTECH, LLC (US) 2023-11-21 — — US disclosed
EP-3122759-B1 CHEMICAL METHODS FOR PRODUCING TAGGED NUCLEOTIDES UNIV COLUMBIA (US) 2022-06-01 — — EP disclosed
US-10240195-B2 Chemical methods for producing tagged nucleotides THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2019-03-26 — — US disclosed
US-20110111462-A1 Composition and Method for Synthesizing a Deoxyribonucleotide Chain Using a Double Stranded Nucleic Acid Complex with a Thermostable Polymerase ENZYMATICS, INC. 2011-05-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110111462-A1 Composition and Method for Synthesizing a Deoxyribonucleotide Chain Using a Double Stranded Nucleic Acid Complex with a Thermostable Polymerase POLN, POLRMT, POLI RNASE1 46/4885TK1 135/4885LMNA 651/4885
US-10240195-B2 Chemical methods for producing tagged nucleotides NT5C3B, NCL, NUDT1 RNASE1 405/4885TK1 333/4885LMNA 1284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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