Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.69 |
| ▸ | TK1 | P04183 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | ALB | P02768 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22992460 | 1.00 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL27989242 | 1.00 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL19132672 | 0.91 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL2056647 | 0.91 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL16359947 | 0.91 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL523267 | 0.91 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL12670320 | 0.91 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL25756080 | 0.91 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL10431982 | 0.91 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB | |
| SCHEMBL523268 | 0.91 | RNASE1 (0.69) | RNASE1TK1LMNATSHRALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005058247-A2 | METHOD FOR PREPARING RADIOLABELED THYMIDINE HAVING LOW CHROMOPHORIC BYPRODUCTS | MOLECULAR TECHNOLOGIES, INC. (US) | 2005-06-30 | — | — | WO | claimed |
| US-20050131223-A1 | Method for preparing radiolabeled thymidine having low chromophoric byproducts | CTI PET SYSTEMS, INC. | 2005-06-16 | — | — | US | claimed |
| US-20090221530-A1 | Relaxase Modulators and Methods of Using Same | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-09-03 | — | — | US | disclosed |
| US-7419653-B2 | Method for preparing radiolabeled thymidine having low chromophoric byproducts | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2008-09-02 | — | — | US | disclosed |
| WO-2007056543-A2 | RELAXASE MODULATORS AND METHODS OF USING SAME | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2007-05-18 | — | — | WO | disclosed |
| US-20070077198-A1 | Method for preparing radiolabeled thymidine having low chromophoric byproducts | WALSH JOSEPH C | 2007-04-05 | — | — | US | disclosed |
| US-7160537-B2 | Method for preparing radiolabeled thymidine having low chromophoric byproducts | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2007-01-09 | — | — | US | disclosed |
| WO-2005058247-A2 | METHOD FOR PREPARING RADIOLABELED THYMIDINE HAVING LOW CHROMOPHORIC BYPRODUCTS | MOLECULAR TECHNOLOGIES, INC. (US) | 2005-06-30 | — | — | WO | disclosed |
| US-20050131223-A1 | Method for preparing radiolabeled thymidine having low chromophoric byproducts | CTI PET SYSTEMS, INC. | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131223-A1 | Method for preparing radiolabeled thymidine having low chromophoric byproducts | TYMP, TYMS, FLT1 | RNASE1 2155/4885TK1 5/4885LMNA 1130/4885 |
| US-20070077198-A1 | Method for preparing radiolabeled thymidine having low chromophoric byproducts | TYMP, TYMS, FLT1 | RNASE1 2155/4885TK1 5/4885LMNA 1130/4885 |
| US-20090221530-A1 | Relaxase Modulators and Methods of Using Same | RXFP1, RXFP2, RXFP4 | RNASE1 50/4885TK1 830/4885LMNA 2581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.