Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.92 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.79 |
| ▸ | NT5E | P21589 | 1/20 | 0.76 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.69 |
| ▸ | BTK | Q06187 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 2/20 | 0.56 |
| ▸ | BRAF | P15056 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29514799 | 0.96 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBPBTK | |
| SCHEMBL23124 | 0.96 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBPBTK | |
| SCHEMBL8381776 | 0.95 | BRD4 (0.97) | BRD4NT5C2NT5ECREBBPBTK | |
| SCHEMBL9230081 | 0.82 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBP | |
| SCHEMBL23683051 | 0.82 | CREBBP (1.00) | BRD4NT5C2NT5ECREBBPTOP2A | |
| SCHEMBL6463473 | 0.80 | BRD4 (0.60) | BRD4NT5C2NT5ECREBBP | |
| SCHEMBL5694204 | 0.79 | BRD4 (0.66) | BRD4NT5C2NT5ECREBBP | |
| SCHEMBL3038563 | 0.78 | NPC1 (0.76) | BRD4NT5C2NT5ECREBBPTOP2A | |
| SCHEMBL22118772 | 0.78 | BRD4 (0.68) | BRD4NT5C2NT5ECREBBPTOP2A | |
| SCHEMBL10644711 | 0.78 | BRD4 (0.68) | BRD4NT5C2NT5ECREBBPTOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193791-A | Modified 2' and 3'-nucleoside produgs for treating flaviridae infections | IDENIX PHARMACEUTICALS INC (US) | 2014-12-10 | — | — | CN | disclosed |
| CN-104163841-A | 2' and 3'-nucleoside prodrugs for treating flaviviridae infections | IDENIX PHARMACEUTICALS INC (US) | 2014-11-26 | — | — | CN | disclosed |
| CN-103319554-A | Modified 2' and 3' -nucleoside produgs for treating flaviridae infections | IDENIX CAYMAN LTD (KY) | 2013-09-25 | — | — | CN | disclosed |
| CN-103275159-A | Modified 2' and 3' -nucleoside produgs for treating flaviridae infections | CENTRE NAT RECH SCIENT (FR) | 2013-09-04 | — | — | CN | disclosed |
| CN-101099745-A | Methods and compositions for treating flaviviruses and pestiviruses | IDENIX CAYMAN LTD (VG) | 2008-01-09 | — | — | CN | disclosed |
| CN-1315862-C | Methods and compositions for treating flaviviruses and pestiviruses | NOVIRIO PHARMACEUTICALS LTD (VG) | 2007-05-16 | — | — | CN | disclosed |
| EP-1523489-A2 | MODIFIED 2' AND 3' -NUCLEOSIDE PRODUGS FOR TREATING FLAVIRIDAE INFECTIONS | Idenix (Cayman) Limited (KY) | 2005-04-20 | — | — | EP | disclosed |
| CN-1468249-A | Methods and compositions for treating flaviviruses and pestiviruses | — | 2004-01-14 | — | — | CN | disclosed |
| WO-2004002999-A2 | MODIFIED 2' AND 3' -NUCLEOSIDE PRODUGS FOR TREATING FLAVIRIDAE INFECTIONS | IDENIX (CAYMAN) LIMITED (KY) | 2004-01-08 | — | — | WO | disclosed |
| EP-1294735-A2 | METHODS AND COMPOSITIONS FOR TREATING FLAVIVIRUSES AND PESTIVIRUSES | Novirio Pharmaceuticals Limited (KY) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001092282-A2 | METHODS AND COMPOSITIONS FOR TREATING FLAVIVIRUSES AND PESTIVIRUSES | IDENIX (CAYMAN) LIMITED (KY) | 2001-12-06 | — | — | WO | disclosed |
| US-4282349-A | Crystalline ribofuranosyl halides and other derivatives and methods for producing same | BOARD OF CONTROL OF MICHIGAN TECHNOLOGICAL UNIVERSITY (US) | 1981-08-04 | — | — | US | disclosed |