Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432660 | 0.90 | CSNK1D (0.39) | HCRTR1 | |
| SCHEMBL10432570 | 0.89 | HCRTR1 (0.41) | HCRTR1TP53EGLN1 | |
| SCHEMBL9586423 | 0.81 | L3MBTL1 (0.41) | HCRTR1HCRTR2SMN1; SMN2JMJD6EGLN1 | |
| Hydrochloric Acid SCHEMBL9586782 | 0.79 | PMP22 (0.41) | HCRTR1HCRTR2SMN1; SMN2JMJD6EGLN1 | |
| SCHEMBL10432627 | 0.79 | WNT1 (0.37) | SMN1; SMN2GABRG2GABRB3GABRA2 | |
| SCHEMBL10432521 | 0.79 | GABRG2 (0.36) | KDM5BGABRG2GABRB3GABRA2 | |
| SCHEMBL10433107 | 0.77 | L3MBTL1 (0.38) | HCRTR1HCRTR2SMN1; SMN2JMJD6L3MBTL1 | |
| SCHEMBL10432601 | 0.74 | KDM4E (0.49) | HCRTR2 | |
| SCHEMBL10432730 | 0.73 | HDAC3 (0.43) | TP53SMN1; SMN2 | |
| SCHEMBL10432788 | 0.72 | CDC25A (0.38) | GABRG2GABRB3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352581-A2 | Ethylene diaminmonoamide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-01-31 | — | — | EP | disclosed |