Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222461 | 0.80 | PLCG1 (0.52) | PLCG1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL30381034 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AGAACA2ALDH1A1 | |
| SCHEMBL9182366 | 0.80 | PLCG1 (0.44) | PLCG1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL27649868 | 0.78 | PLCG1 (0.45) | PLCG1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6602664 | 0.77 | ALDH1A1 (0.42) | PLCG1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6929762 | 0.75 | ALDH1A1 (0.43) | PLCG1GAACA2ALDH1A1MMP2 | |
| SCHEMBL30379216 | 0.75 | PSMD10 (0.41) | MEN1KMT2AGAACA2ALDH1A1 | |
| SCHEMBL19229836 | 0.75 | CA2 (0.46) | PLCG1GAACA2ALDH1A1MMP2 | |
| SCHEMBL18712232 | 0.74 | PLCG1 (0.45) | PLCG1MEN1KMT2AF2PRSS1 | |
| SCHEMBL11249350 | 0.74 | PLCG1 (0.45) | PLCG1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353732-A2 | Fluoro-olefins, method for their preparation and their use | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |