Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 5/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133239 | 0.76 | MAOA (0.49) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL19097592 | 0.72 | MAOA (0.43) | EYA3CYP2C19MAOAMGAMGAA | |
| SCHEMBL29438952 | 0.72 | MAOA (0.43) | EYA3CYP2C19MAOAMGAMGAA | |
| SCHEMBL10585582 | 0.71 | HSP90AA1 (0.53) | CYP2C19GAAMEN1LMNAKMT2A | |
| SCHEMBL9089870 | 0.71 | MAOA (0.39) | CYP2C19MAOAMGAMGAASI | |
| SCHEMBL3119696 | 0.70 | MAOA (0.46) | EYA3CYP2C19MAOAMGAMGAA | |
| SCHEMBL3133235 | 0.70 | MAOA (0.45) | CYP2C19MAOAMGAMGAASI | |
| SCHEMBL26080846 | 0.69 | MAOA (0.41) | EYA3CYP2C19MAOAMGAMGAA | |
| SCHEMBL7866030 | 0.69 | HSP90AA1 (0.48) | EYA3CYP2C19MAOACYP2C9MEN1 | |
| SCHEMBL6695228 | 0.68 | KDM4E (0.59) | CYP2C19MAOACYP2C9MEN1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358774-A1 | NOVEL SPIROOXAZINE COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 1990-03-21 | — | — | EP | disclosed |