Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | NQO1 | P15559 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | PCSK7 | Q16549 | 1/20 | 0.57 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766670 | 0.80 | MAPT (0.59) | KDM4EALDH1A1NQO1MEN1ABCB11 | |
| SCHEMBL11766676 | 0.80 | MAPT (0.59) | KDM4EALDH1A1NQO1MEN1ABCB11 | |
| SCHEMBL29950209 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1NQO1MEN1ABCB11 | |
| SCHEMBL15541690 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1NQO1MEN1ABCB11 | |
| SCHEMBL7737431 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1NQO1MEN1ABCB11 | |
| SCHEMBL29379994 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1NQO1MEN1ABCB11 | |
| SCHEMBL29872 | 0.79 | KDM4E (0.69) | KDM4EALDH1A1NQO1MEN1ABCB11 | |
| SCHEMBL28282771 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1NQO1MEN1ABCB11 | |
| Hydrochloric Acid SCHEMBL8701572 | 0.77 | KDM4E (0.67) | KDM4EALDH1A1NQO1MEN1ABCB11 | |
| SCHEMBL5713261 | 0.76 | KDM4E (0.65) | KDM4EALDH1A1NQO1MEN1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040049859-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | L'OREAL S.A. (FR) | 2004-03-18 | — | — | US | claimed |
| US-20040040098-A1 | Compositions for the oxidation dyeing of keratin fibers and dyeing processes using these compositions | L'OREAL | 2004-03-04 | — | — | US | claimed |
| US-20040025265-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | LANG GERARD (FR) | 2004-02-12 | — | — | US | claimed |
| US-20030159706-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | claimed |
| US-20040049859-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | L'OREAL S.A. (FR) | 2004-03-18 | — | — | US | disclosed |
| US-20040040098-A1 | Compositions for the oxidation dyeing of keratin fibers and dyeing processes using these compositions | L'OREAL | 2004-03-04 | — | — | US | disclosed |
| US-20040025265-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | LANG GERARD (FR) | 2004-02-12 | — | — | US | disclosed |
| US-20040016062-A1 | Nondyeing composition containing a precursor and an oxidation reaction catalyst | L'OREAL (FR) | 2004-01-29 | — | — | US | disclosed |
| EP-1367983-A1 | MICROCAPSULES WITH AQUEOUS CORE CONTAINING OXIDATION-REDUCTION ENZYMES AND THEIR USE IN OXIDATION DYEING COMPOSITIONS | L'OREAL (FR) | 2003-12-10 | — | — | EP | disclosed |
| US-20030159706-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | L'OREAL S.A. (FR) | 2003-08-28 | — | — | US | disclosed |
| EP-1304997-A1 | ENZYME COMPOSITION FOR BLEACHING HUMAN KERATINOUS FIBRES AND BLEACHING METHOD | L'OREAL (FR) | 2003-05-02 | — | — | EP | disclosed |
| EP-1304998-A1 | ENZYME COMPOSITION FOR BLEACHING HUMAN KERATINOUS FIBRES AND BLEACHING METHOD | L'OREAL (FR) | 2003-05-02 | — | — | EP | disclosed |
| EP-1304996-A1 | ENZYME COMPOSITION FOR BLEACHING HUMAN KERATINOUS FIBRES AND BLEACHING METHOD | L'OREAL (FR) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002069922-A1 | MICROCAPSULES WITH AQUEOUS CORE CONTAINING OXIDATION-REDUCTION ENZYMES AND THEIR USE IN OXIDATION DYEING COMPOSITIONS | L'OREAL (FR) | 2002-09-12 | — | — | WO | disclosed |
| WO-2002007689-A1 | ENZYME COMPOSITION FOR BLEACHING HUMAN KERATINOUS FIBRES AND BLEACHING METHOD | L'OREAL (FR) | 2002-01-31 | — | — | WO | disclosed |
| WO-2002007688-A1 | ENZYME COMPOSITION FOR BLEACHING HUMAN KERATINOUS FIBRES AND BLEACHING METHOD | L'OREAL (FR) | 2002-01-31 | — | — | WO | disclosed |
| WO-2002007687-A1 | ENZYME COMPOSITION FOR BLEACHING HUMAN KERATINOUS FIBRES AND BLEACHING METHOD | L'OREAL (FR) | 2002-01-31 | — | — | WO | disclosed |
| EP-0843723-A1 | METHOD FOR ENHANCING THE ACTIVITY OF AN ENZYME, COMPOUNDS SHOWING ENZYME ACTIVITY ENHANCEMENT, AND DETERGENTS CONTAINING SUCH COMPOUNDS | Ciba SC Holding AG (CH) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997006244-A1 | METHOD FOR ENHANCING THE ACTIVITY OF AN ENZYME, COMPOUNDS SHOWING ENZYME ACTIVITY ENHANCEMENT, AND DETERGENTS CONTAINING SUCH COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030159706-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | KRT18, LPO, MPO | KDM4E 354/4885ALDH1A1 347/4885NQO1 326/4885 |
| US-20040025265-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | KRT18, LPO, ALDH1A2 | KDM4E 498/4885ALDH1A1 494/4885NQO1 403/4885 |
| US-20040049859-A1 | Enzyme composition for bleaching human keratinous fibres and bleaching method | KRT18, COXFA4, LPO | KDM4E 403/4885ALDH1A1 322/4885NQO1 452/4885 |
| US-20040040098-A1 | Compositions for the oxidation dyeing of keratin fibers and dyeing processes using these compositions | KRT18, PPOX, POR | KDM4E 766/4885ALDH1A1 164/4885NQO1 34/4885 |
| US-20040016062-A1 | Nondyeing composition containing a precursor and an oxidation reaction catalyst | KRT18, CUTA, PPOX | KDM4E 848/4885ALDH1A1 1106/4885NQO1 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.