Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9089875 | 0.84 | VKORC1 (0.38) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL10433595 | 0.71 | EYA3 (0.45) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL3133239 | 0.66 | MAOA (0.49) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL4578929 | 0.62 | IDO1 (0.50) | SMN1; SMN2 | |
| SCHEMBL18092268 | 0.60 | ALDH1A1 (0.36) | GAARAB9ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL3133235 | 0.60 | MAOA (0.45) | MAOAMGAMGAASIMGAM2 | |
| SCHEMBL28648891 | 0.60 | MAOA (0.38) | MAOARAB9ASMN1; SMN2HPGDNPC1 | |
| Hydroquinone SCHEMBL10824379 | 0.59 | HSD17B10 (0.40) | RAB9ASMN1; SMN2HPGDNPC1CYP1A2 | |
| SCHEMBL20609463 | 0.59 | HTR2A (0.43) | SMN1; SMN2HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2963907 | 0.59 | ALDH1A1 (0.45) | MAOARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559231-A | PHOTOCHROMIC, RECORDING MATERIAL, CLOTHING, GLASSES, WINDOWS | TORAY INDUSTRIES, INC. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0358774-B1 | NOVEL SPIROOXAZINE COMPOUNDS | TORAY INDUSTRIES (JP) | 1995-10-25 | — | — | EP | disclosed |
| US-5374723-A | Photochromic dyes; resistance to repetition of coloration and discoloration | TORAY INDUSTRIES, INC. (JP) | 1994-12-20 | — | — | US | disclosed |