Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28669740 | 0.87 | ALDH1A1 (0.49) | F7F3GPR84NR4A2IDO1 | |
| SCHEMBL10433676 | 0.81 | MEN1 (0.48) | NR4A2HTR2AIDO1CDK4CCND1 | |
| SCHEMBL10433671 | 0.81 | NPSR1 (0.49) | HTR2AIDO1MGLLALDH1A1HSP90AA1 | |
| SCHEMBL10433672 | 0.81 | TSHR (0.48) | GPR84HTR2ATRPM8IDO1CDK4 | |
| SCHEMBL10433692 | 0.81 | HPGD (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10433675 | 0.77 | KDM4E (0.41) | MGLLALDH1A1NPSR1TLR9MAPT | |
| SCHEMBL10433678 | 0.77 | CYP1A2 (0.52) | GPR84NR4A2HTR2ATRPM8IDO1 | |
| SCHEMBL10433700 | 0.77 | HTR3E (0.45) | POLBHTR2AIDO1TUBB4ATUBB | |
| SCHEMBL10433666 | 0.77 | IDO1 (0.46) | IDO1ALDH1A1HSP90AA1NPSR1TLR9 | |
| SCHEMBL856333 | 0.76 | TLR9 (0.52) | GPR84CDK4CCND1MGLLATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | disclosed |