Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 8/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
| ▸ | PRKACB | P22694 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27519391 | 0.82 | MGLL (0.51) | TLR9MGLLSIRT2SIRT1PRKD3 | |
| SCHEMBL3044022 | 0.80 | SMN1; SMN2 (0.43) | SIRT2SIRT1PRKD3CCNB2CCNE2 | |
| SCHEMBL30688235 | 0.80 | SMN1; SMN2 (0.43) | SIRT2SIRT1PRKD3CCNB2CCNE2 | |
| SCHEMBL31727125 | 0.77 | SMN1; SMN2 (0.48) | SIRT2SIRT1PRKD3CCNB2CCNE2 | |
| SCHEMBL27910874 | 0.77 | SIRT2 (0.41) | SIRT2SIRT1PRKD3CCNB2CCNE2 | |
| SCHEMBL7198015 | 0.77 | SIRT2 (0.44) | TLR9MGLLSIRT2SIRT1PRKD3 | |
| SCHEMBL28340162 | 0.76 | TLR9 (0.50) | TLR9MGLLMAPTAHR | |
| SCHEMBL10433673 | 0.76 | F7 (0.49) | TLR9MGLLCDK4CCND1GPR84 | |
| SCHEMBL10433671 | 0.76 | NPSR1 (0.49) | MGLLMEN1CYP3A4MAPTKMT2A | |
| SCHEMBL10433692 | 0.76 | HPGD (0.42) | TLR9MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 486 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117276670-A | Lithium ion battery electrolyte and lithium ion battery | 湖州耀宁固态电池研究院有限公司 | 2023-12-22 | — | — | CN | claimed |
| US-20200385685-A1 | ROBUST DIFFERENTIATION OF HUMAN PLURIPOTENT STEM CELLS INTO ENDOTHELIAL CELLS USING TRANSCRIPTION FACTOR ETV2 | CHILDREN'S MEDICAL CENTER CORPORATION | 2020-12-10 | — | — | US | claimed |
| CN-105153126-A | Preparation method of bisindolyl maleimide compounds | NAT UNIV DONG HWA | 2015-12-16 | — | — | CN | claimed |
| EP-2928466-A1 | USE OF MALEIMIDE DERIVATIVES FOR PREVENTING AND TREATING LEUKEMIA | Centogene AG (DE) | 2015-10-14 | — | — | EP | claimed |
| CN-103998444-A | Adhesive agent | CANCER THERAPEUTICS CRC PTY LTD | 2014-08-20 | — | — | CN | claimed |
| WO-2014090398-A1 | USE OF MALEIMIDE DERIVATIVES FOR PREVENTING AND TREATING LEUKEMIA | CENTOGENE AG (DE) | 2014-06-19 | — | — | WO | claimed |
| CN-101671329-B | Indolylmaleimide compound substituted with 3-amino alcohol, preparation method and application thereof | UNIV DONGHUA | 2012-11-07 | — | — | CN | claimed |
| EP-2305274-A1 | Use of WNT stimulators for treating demyelinating diseases | Centre National de la Recherche Scientifique (CNRS) (FR) | 2011-04-06 | — | — | EP | claimed |
| CN-101671329-A | Indolylmaleimide compound substituted with 3-amino alcohol, preparation method and application thereof | UNIV DONGHUA | 2010-03-17 | — | — | CN | claimed |
| US-20090306045-A1 | Inhibition of Glycogen Synthase Kinase and Methods of Treating Autoimmune or Immune Inflammatory Disease | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-12-10 | — | — | US | claimed |
| WO-2003104482-A1 | SIGNALS AND MOLECULAR SPECIES INVOLVED IN SENESCENCE | METABOLIC ENGINEERING LABORATORIES CO., LTD. (KR) | 2003-12-18 | — | — | WO | claimed |
| US-20030143185-A1 | Polymer conjugates of protein kinase C inhibitors | SHEARWATER CORPORATION | 2003-07-31 | — | — | US | claimed |
| WO-2003037384-A2 | POLYMER CONJUGATES OF PROTEIN KINASE C INHIBITORS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2003-05-08 | — | — | WO | claimed |
| EP-1224932-A1 | DRUGS INHIBITING CELL DEATH | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2002-07-24 | — | — | EP | claimed |
| EP-0888339-A4 | SYNTHESIS OF INDOLYLMALEIMIDES | LILLY CO ELI (US) | 2001-02-28 | — | — | EP | claimed |
| US-5919946-A | REACTING AN ACTIVATED MALEIMIDE WITH AN ORGANOMETALLIC-3-INDOLE IN PRESENCE OF A PALLADIUM TRANSITION METAL CATALYST | ELI LILLY AND COMPANY (US) | 1999-07-06 | — | — | US | claimed |
| US-5859261-A | PROTEIN KINASE INHIBITORS | ELI LILLY AND COMPANY (US) | 1999-01-12 | — | — | US | claimed |
| EP-0888339-A1 | SYNTHESIS OF INDOLYLMALEIMIDES | ELI LILLY AND COMPANY (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034890-A1 | SYNTHESIS OF INDOLYLMALEIMIDES | ELI LILLY AND COMPANY (US) | 1997-09-25 | — | — | WO | claimed |
| EP-0397060-A2 | Maleinimide derivatives and their use as medicines | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1990-11-14 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030143185-A1 | Polymer conjugates of protein kinase C inhibitors | PRKCH, PRKCI, PRKCA | TLR9 1894/4885MGLL 1714/4885DNMT1 1697/4885 |
| US-20090306045-A1 | Inhibition of Glycogen Synthase Kinase and Methods of Treating Autoimmune or Immune Inflammatory Disease | GSK3B, GSK3A, GSKIP | TLR9 68/4885MGLL 2289/4885DNMT1 1468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.