Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27322903 | 1.00 | KEAP1 (0.45) | KEAP1HSPA5TSHRHIF1AALDH1A1 | |
| SCHEMBL8368533 | 0.81 | HDAC1 (0.46) | HIF1AALDH1A1LMNAHDAC1NPC1 | |
| SCHEMBL8954802 | 0.81 | HDAC1 (0.46) | HIF1AALDH1A1LMNAHDAC1NPC1 | |
| SCHEMBL563939 | 0.79 | TSHR (0.47) | TSHRHIF1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8819049 | 0.79 | TSHR (0.47) | TSHRHIF1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8539430 | 0.79 | TSHR (0.47) | TSHRHIF1AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3370230 | 0.78 | LMNA (0.51) | TSHRHIF1AALDH1A1TP53CYP1A2 | |
| SCHEMBL2579068 | 0.78 | KEAP1 (0.56) | KEAP1HSPA5TSHRHIF1AALDH1A1 | |
| SCHEMBL3370228 | 0.78 | LMNA (0.51) | TSHRHIF1AALDH1A1TP53CYP1A2 | |
| SCHEMBL5195934 | 0.78 | LMNA (0.51) | TSHRHIF1AALDH1A1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398692-A2 | Alkoxyiminoacetamide derivatives and their use as fungicides | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1990-11-22 | — | — | EP | disclosed |