Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5195934 | 1.00 | LMNA (0.51) | LMNATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL3370228 | 1.00 | LMNA (0.51) | LMNATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL7745166 | 0.86 | TSHR (0.41) | LMNATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL8846269 | 0.84 | NPC1 (0.41) | LMNAKDM4EHPGDALDH1A1HIF1A | |
| SCHEMBL8846279 | 0.84 | NPC1 (0.41) | LMNAKDM4EHPGDALDH1A1HIF1A | |
| SCHEMBL6705432 | 0.83 | LMNA (0.55) | LMNATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL7119395 | 0.83 | LMNA (0.55) | LMNATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL6705433 | 0.83 | LMNA (0.55) | LMNATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL8761028 | 0.83 | SIRT2 (0.38) | LMNATSHRKDM4EHPGDALDH1A1 | |
| SCHEMBL7221644 | 0.82 | LMNA (0.42) | LMNATSHRKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268446-B1 | METHOD FOR PRODUCING ASYMMETRICAL 4,6-BIS(ARYLOXY)PYRIMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-10-06 | — | — | EP | disclosed |
| EP-0937050-B1 | HALOGEN PYRIMIDINYL ARYL (THIO)ETHERS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2007-08-08 | — | — | EP | disclosed |
| CN-1618792-A | Method of producing methoxyimino acetic amide | BAYER AG (DE) | 2005-05-25 | — | — | CN | disclosed |
| US-6831197-B2 | Intermediates, in particular for preparing fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-12-14 | — | — | US | disclosed |
| EP-1185505-B1 | METHOD OF PRODUCING METHOXYIMINO ACETIC AMIDE | BAYER CROPSCIENCE AG (DE) | 2004-11-03 | — | — | EP | disclosed |
| US-20040199014-A1 | Method for producing 2-(hydroxyphenyl)-2-(alkoxyimino)-n-methylacetamide derivatives | BAYER CROPSCIENCE AG (DE) | 2004-10-07 | — | — | US | disclosed |
| US-20040186318-A1 | Method for producing (2e)-2-(hydroxyphenyl-2-(alkoxyimino)-n-methylacetamides | BAYER CROPSCIENCE AG (DE) | 2004-09-23 | — | — | US | disclosed |
| CN-1160313-C | Process for preparing methoxyiminoacetamide | — | 2004-08-04 | — | — | CN | disclosed |
| US-20040147782-A1 | Methods for producing 2-(2-hydroxyphenyl)-2-(alkoxyimino)-N-methylacetamide derivatives | HUBSCH WALTER (DE) | 2004-07-29 | — | — | US | disclosed |
| EP-1417168-A2 | METHOD FOR PRODUCING 2-(HYDROXYPHENYL)-2-(ALKOXYIMINO)-N-METHYLACETAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2004-05-12 | — | — | EP | disclosed |
| EP-0937050-A1 | HALOGEN PYRIMIDINYL ARYL (THIO)ETHERS AS PESTICIDES | BAYER AG (DE) | 1999-08-25 | — | — | EP | disclosed |
| WO-1999005122-A1 | PYRIMIDYL OXYPHENYLACETIC ACID DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-04 | — | — | WO | disclosed |
| WO-1998021189-A1 | HALOGEN PYRIMIDINYL ARYL (THIO)ETHERS AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-05-22 | — | — | WO | disclosed |
| EP-0398692-B1 | Alkoxyiminoacetamide derivatives and their use as fungicides | SHIONOGI & CO (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5548078-A | FOR AGRICULTURE | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1996-08-20 | — | — | US | disclosed |
| US-5401877-A | Agricultural fungicide | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0629609-A1 | Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5371223-A | Controlling phytopathogens | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5371222-A | Intermediates | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5185342-A | ALKOXYIMINOACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186318-A1 | Method for producing (2e)-2-(hydroxyphenyl-2-(alkoxyimino)-n-methylacetamides | HMOX2, CYP1A2, PTGS2 | LMNA 1227/4885TSHR 4445/4885KDM4E 1620/4885 |
| US-20040199014-A1 | Method for producing 2-(hydroxyphenyl)-2-(alkoxyimino)-n-methylacetamide derivatives | HMOX2, AADAC, HNMT | LMNA 788/4885TSHR 4296/4885KDM4E 2496/4885 |
| US-20040147782-A1 | Methods for producing 2-(2-hydroxyphenyl)-2-(alkoxyimino)-N-methylacetamide derivatives | AADAC, HACL2, AZI2 | LMNA 1724/4885TSHR 4354/4885KDM4E 3677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.