Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787665 | 0.84 | KCNA5 (0.42) | HSD11B1HPGDSMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL6060766 | 0.72 | HPGD (0.38) | HSD11B1HPGDSMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL3787614 | 0.71 | HPGD (0.36) | HSD11B1HPGDRECQLGAASMN1; SMN2 | |
| SCHEMBL1044264 | 0.70 | L3MBTL1 (0.42) | HSD11B1HPGDGAASMN1; SMN2CYP1A2 | |
| SCHEMBL20825349 | 0.68 | HRH1 (0.47) | HSD11B1GAASMN1; SMN2CYP1A2NPC1 | |
| SCHEMBL25867869 | 0.68 | HRH3 (0.50) | HSD11B1CYP1A2CYP2C19L3MBTL1ALDH1A1 | |
| SCHEMBL6060418 | 0.68 | CYP1A2 (0.33) | CYP1A2 | |
| SCHEMBL23881997 | 0.68 | GAA (0.47) | HSD11B1HPGDRECQLGAASMN1; SMN2 | |
| SCHEMBL31446462 | 0.65 | PTPRA (0.47) | GAASMN1; SMN2CYP1A2CYP2C19NPC1 | |
| SCHEMBL3988369 | 0.65 | HPGD (0.49) | HSD11B1HPGDRECQLGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272826-A1 | 2-mercaptopentancarboxylic acid derivatives, the method for preparing them and the pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-01-12 | — | — | EP | disclosed |
| WO-2010149888-A1 | DERIVATIVES OF 2-MERCAPTOCYCLOPENTANE CARBOXYLIC ACID, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | LES LABORATOIRES SERVIER (FR) | 2010-12-29 | — | — | WO | disclosed |