Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788196 | 0.84 | DDB1 (0.42) | GAASMN1; SMN2CYP1A2CYP2C19RAB9A | |
| SCHEMBL10798557 | 0.71 | TACR3 (0.39) | L3MBTL1HSD11B1HPGD | |
| SCHEMBL15353048 | 0.71 | DDB1 (0.40) | L3MBTL1GAASMN1; SMN2PTPRACPB2 | |
| SCHEMBL1043392 | 0.70 | HSD11B1 (0.43) | L3MBTL1GAASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL20825349 | 0.69 | HRH1 (0.47) | L3MBTL1GAASMN1; SMN2CYP1A2RAB9A | |
| SCHEMBL8575486 | 0.69 | — | — | |
| SCHEMBL6060737 | 0.69 | SIRT2 (0.33) | CYP2C19POLB | |
| SCHEMBL23881997 | 0.69 | GAA (0.47) | L3MBTL1GAASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL18440292 | 0.67 | TACR1 (0.44) | L3MBTL1CYP2C19POLB | |
| SCHEMBL6060679 | 0.66 | SIRT2 (0.38) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272826-A1 | 2-mercaptopentancarboxylic acid derivatives, the method for preparing them and the pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2011-01-12 | — | — | EP | disclosed |
| WO-2010149888-A1 | DERIVATIVES OF 2-MERCAPTOCYCLOPENTANE CARBOXYLIC ACID, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | LES LABORATOIRES SERVIER (FR) | 2010-12-29 | — | — | WO | disclosed |