Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042314 | 0.84 | NAPRT (0.44) | HSD11B1ALDH1A1KDM4EHTTSMN1; SMN2 | |
| SCHEMBL4808147 | 0.84 | ADAM17 (0.47) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4807305 | 0.82 | KDM4E (0.51) | ALDH1A1KDM4ELMNASMN1; SMN2OPRM1 | |
| SCHEMBL4580682 | 0.77 | LTB4R (0.36) | HPGDHSD11B1EPHX1ALDH1A1LMNA | |
| SCHEMBL7447229 | 0.75 | KDM4E (0.40) | HPGDEPHX1ALDH1A1EPHX2KDM4E | |
| SCHEMBL18494342 | 0.73 | MAPT (0.41) | ALDH1A1KDM4ELMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL1841591 | 0.73 | LMNA (0.46) | HPGDMAOAMAOBHSD11B1ALDH1A1 | |
| SCHEMBL9314420 | 0.73 | HSD11B1 (0.41) | HPGDMAOAMAOBHSD11B1 | |
| SCHEMBL3781275 | 0.72 | CYP17A1 (0.49) | LMNA | |
| SCHEMBL1043392 | 0.72 | HSD11B1 (0.43) | HPGDHSD11B1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006045246-A1 | CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2006-05-04 | — | — | WO | disclosed |