Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.71 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 6/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.69 |
| ▸ | ALB | P02768 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.66 |
| ▸ | TUBB | P07437 | 1/20 | 0.66 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.66 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.66 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.66 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.66 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.66 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.66 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.66 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.66 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434082 | 1.00 | KDM4E (0.71) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL8921051 | 0.89 | TOP2A (0.60) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL11035249 | 0.88 | KDM4E (0.55) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9866854 | 0.87 | KDM4E (0.68) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL10433860 | 0.83 | TOP2A (0.70) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL10433916 | 0.83 | TOP2A (0.70) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL10727411 | 0.83 | TOP2A (0.70) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL9581753 | 0.83 | KDM4E (0.71) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL9034716 | 0.83 | KDM4E (0.71) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL9582683 | 0.83 | KDM4E (0.71) | KDM4EADRA2BMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |