Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10434007 | 0.88 | KDM4E (0.71) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL10434082 | 0.88 | KDM4E (0.71) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL11160975 | 0.83 | KDM4E (0.57) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL11162090 | 0.81 | LMNA (0.64) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL9703884 | 0.81 | KDM4E (0.55) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL11080275 | 0.80 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL8435558 | 0.80 | ALDH1A1 (0.58) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL8921051 | 0.78 | TOP2A (0.60) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL10733184 | 0.77 | TOP2A (0.67) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL10433914 | 0.77 | TOP2A (0.67) | KDM4EADRA2BMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59076091-A | — | — | None | — | — | JP | disclosed |
| JP-S5976091-A | PYRIDO (1,2,3-DE)(1,4)BENZOTHIAZINE DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1984-04-28 | — | — | JP | disclosed |