Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690292 | 0.86 | L3MBTL1 (0.50) | APPABCB1ABCG2ALOX5KDM4E | |
| SCHEMBL9217221 | 0.85 | ALDH1A1 (0.52) | APPABCB1ABCG2ALDH1A1CETP | |
| SCHEMBL12963323 | 0.84 | ABCB1 (0.73) | APPABCB1RXRAMRGPRX4ATM | |
| SCHEMBL9615215 | 0.82 | MRGPRX4 (0.69) | APPABCB1RXRAMRGPRX4ATM | |
| SCHEMBL9597779 | 0.81 | RAB9A (0.64) | ALDH1A1MAPTRAB9A | |
| SCHEMBL2839320 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPTRAB9ACYP1A2 | |
| SCHEMBL5198075 | 0.80 | MAPT (0.51) | MRGPRX4MAPTRAB9ACETP | |
| SCHEMBL10854605 | 0.79 | APP (0.60) | APPALOX5ALDH1A1MAPTRAB9A | |
| SCHEMBL9598981 | 0.79 | RAB9A (0.50) | ATMALOX5ALDH1A1MAPTRAB9A | |
| SCHEMBL28440304 | 0.78 | RAB9A (0.49) | MRGPRX4ALOX5ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375368-A2 | Alcohol and ether derivatives | ZENECA LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |