Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10435945 | 0.94 | CYP2C19 (0.52) | MAOACYP2C19CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL6306047 | 0.89 | CYP2C19 (0.59) | CYP2C19CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL28965534 | 0.87 | CYP2C19 (0.57) | CYP2C19CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL68470 | 0.85 | CYP2C19 (0.68) | CYP2C19CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL7909121 | 0.84 | CYP2C19 (0.59) | CYP2C19CYP1A2CYP2D6CYP3A4CYP2C9 | |
| Bromide SCHEMBL11187006 | 0.83 | CYP2C19 (0.65) | CYP2C19CYP1A2CYP2D6CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL1466264 | 0.83 | CYP2C19 (0.65) | CYP2C19CYP1A2CYP2D6CYP3A4CYP2C9 | |
| SCHEMBL6682623 | 0.82 | CYP2C19 (0.66) | MAOACYP2C19CYP1A2CYP2D6CYP3A4 | |
| Glycolic Acid SCHEMBL11647705 | 0.82 | CYP2C19 (0.59) | MAOACYP2C19CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL11935009 | 0.81 | SIGMAR1 (0.49) | MAOASMN1; SMN2ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250099384-A1 | THIOESTER CATIONIC LIPIDS | TRANSLATE BIO INC (US) | 2025-03-27 | — | — | US | disclosed |
| US-12076439-B2 | Thioester cationic lipids | TRANSLATE BIO, INC. (US) | 2024-09-03 | — | — | US | disclosed |
| CN-117430538-A | Thioester cationic lipids | 川斯勒佰尔公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437767-B | thioester cationic lipids | 川斯勒佰尔公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20220008338-A1 | Thioester Cationic Lipids | TRANSLATE BIO, INC. | 2022-01-13 | — | — | US | disclosed |
| US-20220008338-A1 | Thioester Cationic Lipids | TRANSLATE BIO, INC. | 2022-01-13 | — | — | US | disclosed |
| EP-3802487-A1 | THIOESTER CATIONIC LIPIDS | Translate Bio, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| CN-112437767-A | Thioester cationic lipids | 川斯勒佰尔公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-105237451-A | Thioether allyl isothiocyanate compounds, and preparation method and applications thereof | UNIV HAINAN NORMAL | 2016-01-13 | — | — | CN | disclosed |
| US-4933369-A | ANALGESICS | G. D. SEARLE & CO. (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0361482-A1 | Dimethyl tyrosyl amide sulfides, sulfoxides and sulfones | G.D. Searle & Co. (US) | 1990-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12076439-B2 | Thioester cationic lipids | CETP, LYPLA2, LYPLA1 | MAOA 4299/4885CYP2C19 4595/4885CYP1A2 4730/4885 |
| US-20250099384-A1 | THIOESTER CATIONIC LIPIDS | CETP, LYPLA2, LYPLA1 | MAOA 4299/4885CYP2C19 4595/4885CYP1A2 4730/4885 |
| US-20220008338-A1 | Thioester Cationic Lipids | CETP, LYPLA2, LYPLA1 | MAOA 4299/4885CYP2C19 4595/4885CYP1A2 4730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.