SCHEMBL10436833

SCHEMBL10436833

O=Cc1c(O)nc2ccc(Cl)cc2c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 3/20 0.43
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 2/20 0.40
PTGES O14684 1/20 0.40
ALOX5 P09917 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40
CASP7 P55210 1/20 0.40
HIF1A Q16665 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NPFFR1 Q9GZQ6 1/20 0.39
NPFFR2 Q9Y5X5 1/20 0.39
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
POLB P06746 1/20 0.38
RECQL P46063 1/20 0.38
CASP6 P55212 1/20 0.38
PADI4 Q9UM07 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11429929 0.87 POLB (0.44) ERN1TDP1ALDH1A1HPGDKDM4E
SCHEMBL11414734 0.84 ERN1 (0.51) ERN1TDP1ALDH1A1HSD17B10NPFFR1
SCHEMBL10436994 0.81 ALB (0.47) ERN1ALDH1A1HSD17B10KDM4EL3MBTL1
SCHEMBL10436845 0.80 PADI4 (0.35) ERN1TDP1ALDH1A1KDM4EPADI4
SCHEMBL27659545 0.79 POLB (0.51) TDP1ALDH1A1PTGESALOX5CYP2C9
SCHEMBL10538034 0.77 KMT2A (0.43) ALDH1A1HPGDHSD17B10KDM4EL3MBTL1
SCHEMBL11421687 0.76 KMT2A (0.48) TDP1ALDH1A1PTGESALOX5CYP2C9
SCHEMBL8083606 0.76 ERN1 (0.60) ERN1TDP1ALDH1A1HPGDCASP7
SCHEMBL11429100 0.74 ERN1 (0.43) ERN1ALDH1A1CYP2C9HSD17B10RECQL
SCHEMBL11417217 0.72 ERN1 (0.37) ERN1TDP1ALDH1A1CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0354178-A1 Thermoplastics containing a metal complex pigment CIBA-GEIGY AG (CH) 1990-02-07 EP disclosed
US-4866112-A BISAZOLMETHINE WITH DIOXYQUINOLINYL RADICALS AS LIGAND CIBA-GEIGY CORPORATION (US) 1989-09-12 US disclosed
US-4237286-A COLORING PLASTICS AND LACQUERS IN YELLOW TO RED SHADES CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
US-4237292-A SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
US-4237293-A COLORFAST SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
US-4144258-A ORGANIC PIGMENTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1979-03-13 US disclosed
US-4132708-A Metal complexes of azomethines and process for their manufacture CIBA-GEIGY CORPORATION (US) 1979-01-02 US disclosed
US-4111947-A DYES, PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1978-09-05 US disclosed
US-4065481-A 1:1-Azomethine-metal-complex dyestuffs CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4024132-A Azomethine pigments CIBA-GEIGY CORPORATION (US) 1977-05-17 US disclosed
US-4022770-A COLORING CIBA-GEIGY CORPORATION (US) 1977-05-10 US disclosed
US-3988323-A PIGMENTS CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed
US-3974149-A TONERS CIBA-GEIGY CORPORATION (US) 1976-08-10 US disclosed