SCHEMBL11414734

SCHEMBL11414734

Cc1nc2ccc(Cl)cc2c(O)c1C=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 2/20 0.51
FABP3 P05413 1/20 0.47
FABP4 P15090 1/20 0.47
KDM4E B2RXH2 3/20 0.44
MPO P05164 1/20 0.43
NPFFR1 Q9GZQ6 1/20 0.43
NPFFR2 Q9Y5X5 1/20 0.43
PLA2G2A P14555 2/20 0.43
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
USP2 O75604 1/20 0.42
MAPT P10636 1/20 0.42
HSD17B10 Q99714 1/20 0.42
DHODH Q02127 2/20 0.41
HSP90AB1 P08238 1/20 0.40
LMNA P02545 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10436833 0.84 ERN1 (0.43) ERN1FABP3FABP4KDM4ENPFFR1
SCHEMBL11416622 0.79 TRIM24 (0.50) ERN1KDM4EPLA2G2AALDH1A1KMT2A
SCHEMBL2126008 0.79 KDM4E (0.51) FABP3FABP4KDM4EMPONPFFR1
SCHEMBL30351054 0.78 FABP3 (0.46) FABP3FABP4KDM4EMPONPFFR1
SCHEMBL25204459 0.78 FABP3 (0.46) FABP3FABP4KDM4EMPONPFFR1
SCHEMBL11416237 0.78 ERN1 (0.76) ERN1KDM4EALDH1A1KMT2AMEN1
SCHEMBL10656381 0.75 FABP3 (0.50) FABP3FABP4KDM4EPLA2G2ADHODH
SCHEMBL15491613 0.74 FABP3 (0.62) FABP3FABP4KDM4EPLA2G2AALDH1A1
SCHEMBL10657576 0.73 LMNA (0.64) ERN1FABP3FABP4KDM4EPLA2G2A
SCHEMBL15491612 0.73 FABP3 (0.47) FABP3FABP4KDM4EMPONPFFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4237293-A COLORFAST SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
US-4237286-A COLORING PLASTICS AND LACQUERS IN YELLOW TO RED SHADES CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
US-4237292-A SHADES OF YELLOW TO RED FOR PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1980-12-02 US disclosed
US-4144258-A ORGANIC PIGMENTS FOR POLYMERS CIBA-GEIGY CORPORATION (US) 1979-03-13 US disclosed
US-4132708-A Metal complexes of azomethines and process for their manufacture CIBA-GEIGY CORPORATION (US) 1979-01-02 US disclosed
US-4111947-A DYES, PLASTICS, LACQUERS CIBA-GEIGY CORPORATION (US) 1978-09-05 US disclosed
US-4065481-A 1:1-Azomethine-metal-complex dyestuffs CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4024132-A Azomethine pigments CIBA-GEIGY CORPORATION (US) 1977-05-17 US disclosed
US-4022770-A COLORING CIBA-GEIGY CORPORATION (US) 1977-05-10 US disclosed
US-4016157-A COLORING PLASTICS AND LACQUERS CIBA-GEIGY CORPORATION (US) 1977-04-05 US disclosed
US-3988323-A PIGMENTS CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed
US-3974149-A TONERS CIBA-GEIGY CORPORATION (US) 1976-08-10 US disclosed