Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536094 | 0.84 | KMT2A (0.45) | KMT2AMAPTMAOBALDH1A1MEN1 | |
| SCHEMBL10536051 | 0.83 | KMT2A (0.54) | KMT2AMAPTMAOBALDH1A1MEN1 | |
| SCHEMBL11907327 | 0.83 | KMT2A (0.54) | KMT2AMAPTMAOBALDH1A1MEN1 | |
| SCHEMBL30196788 | 0.83 | KMT2A (0.54) | KMT2AMAPTMAOBALDH1A1MEN1 | |
| SCHEMBL11974118 | 0.83 | KMT2A (0.54) | KMT2AMAPTMAOBALDH1A1MEN1 | |
| SCHEMBL10436833 | 0.77 | ERN1 (0.43) | KMT2AHSD17B10HPGDALDH1A1MEN1 | |
| SCHEMBL24213316 | 0.75 | MAPT (0.45) | KMT2AMAPTMAOBALDH1A1MEN1 | |
| SCHEMBL30196628 | 0.75 | MAPT (0.45) | KMT2AMAPTMAOBALDH1A1MEN1 | |
| SCHEMBL23668744 | 0.75 | MAPT (0.45) | KMT2AMAPTMAOBALDH1A1MEN1 | |
| SCHEMBL17153341 | 0.74 | ALDH1A1 (0.47) | KMT2AMAPTHPGDMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4866112-A | BISAZOLMETHINE WITH DIOXYQUINOLINYL RADICALS AS LIGAND | CIBA-GEIGY CORPORATION (US) | 1989-09-12 | — | — | US | disclosed |