Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrobenzene SCHEMBL10437459 | 0.87 | CXCR2 (0.42) | HPGDALOX12L3MBTL1LMNASMN1; SMN2 | |
| Nitrobenzene SCHEMBL10437450 | 0.84 | AKR1C3 (0.48) | HPGDALOX12L3MBTL1SMN1; SMN2MAPT | |
| Nitrobenzene SCHEMBL10437455 | 0.81 | MEN1 (0.46) | HPGDALOX12L3MBTL1SMN1; SMN2HTT | |
| Nitrobenzene SCHEMBL10437476 | 0.80 | HPGD (0.44) | HPGDALOX12L3MBTL1LMNASMN1; SMN2 | |
| Nitrobenzene SCHEMBL10437487 | 0.80 | MAPT (0.48) | L3MBTL1LMNASMN1; SMN2MAPTMAPK14 | |
| SCHEMBL4225477 | 0.71 | MAPK14 (0.64) | MAPK14 | |
| SCHEMBL4220114 | 0.70 | MAPK14 (0.68) | SMN1; SMN2MAPTMAPK14ALDH1A1NPC1 | |
| Nitrobenzene SCHEMBL8098284 | 0.67 | ALDH1A1 (0.76) | HPGDALOX12L3MBTL1LMNASMN1; SMN2 | |
| Nitrobenzene SCHEMBL3465396 | 0.67 | ALDH1A1 (0.76) | HPGDALOX12L3MBTL1LMNASMN1; SMN2 | |
| Benzene SCHEMBL7148507 | 0.67 | KMT2A (0.50) | HPGDL3MBTL1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360566-A2 | Lipoxygenase/cyclooxygenase inhibiting benzoxazolones | PFIZER INC. (US) | 1990-03-28 | — | — | EP | disclosed |