Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrobenzene SCHEMBL10437455 | 0.86 | MEN1 (0.46) | MAPTMEN1KMT2AALDH1A1PKM | |
| Nitrobenzene SCHEMBL10437450 | 0.84 | AKR1C3 (0.48) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL2320736 | 0.82 | MAPK14 (0.60) | MAPTRECQLDUSP3PTPN5PTPN11 | |
| Nitrobenzene SCHEMBL10437430 | 0.80 | HPGD (0.44) | MAPTMEN1KMT2AALDH1A1MAPK14 | |
| Nitrobenzene SCHEMBL10437459 | 0.79 | CXCR2 (0.42) | MAPTMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL3397565 | 0.78 | MAPT (0.64) | MAPTRECQLDUSP3PTPN5PTPN11 | |
| SCHEMBL2314733 | 0.72 | MAPK14 (0.65) | MAPK14 | |
| SCHEMBL2316272 | 0.70 | MAPK14 (0.70) | MAPK14 | |
| SCHEMBL11331546 | 0.68 | MAPT (0.62) | MAPTRECQLDUSP3PTPN5PTPN11 | |
| SCHEMBL10437485 | 0.67 | CTSV (0.60) | MAPTMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360566-A2 | Lipoxygenase/cyclooxygenase inhibiting benzoxazolones | PFIZER INC. (US) | 1990-03-28 | — | — | EP | disclosed |