Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.64 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13265979 | 0.85 | KMT2A (0.67) | MAPTPKMMAPK1ALDH1A1MEN1 | |
| SCHEMBL11344666 | 0.84 | ALDH1A1 (0.58) | MAPTPKMRECQLDUSP3PTPN5 | |
| SCHEMBL5923796 | 0.83 | MAPT (0.81) | MAPTRECQLMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL11331546 | 0.82 | MAPT (0.62) | MAPTPKMRECQLDUSP3PTPN5 | |
| SCHEMBL28401848 | 0.80 | ALDH1A1 (0.73) | MAPTMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL2309092 | 0.80 | MAPT (0.74) | MAPTPKMRECQLDUSP3PTPN5 | |
| SCHEMBL11025851 | 0.79 | L3MBTL1 (0.62) | MAPTPKMRECQLMAPK1ALDH1A1 | |
| SCHEMBL30499873 | 0.79 | L3MBTL1 (0.62) | MAPTPKMRECQLMAPK1ALDH1A1 | |
| Nitrobenzene SCHEMBL10437487 | 0.78 | MAPT (0.48) | MAPTPKMRECQLDUSP3PTPN5 | |
| SCHEMBL7993363 | 0.78 | ALDH1A1 (0.54) | MAPTPKMRECQLDUSP3PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247558-A1 | NOVEL IMAGING AGENTS FOR DETECTING NEUROLOGICAL DYSFUNCTION | Siemens Medical Solutions USA, Inc. (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009102498-A1 | NOVEL IMAGING AGENTS FOR DETECTING NEUROLOGICAL DYSFUNCTION | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2009-08-20 | — | — | WO | disclosed |
| US-4304939-A | Preparation of N-phenyl-N-alkylphenylenediamines | UOP INC. (US) | 1981-12-08 | — | — | US | disclosed |
| EP-0011790-B1 | PROCESS FOR THE PREPARATION OF NITRODIPHENYL AMINE DERIVATIVES | BAYER AG (DE) | 1981-07-15 | — | — | EP | disclosed |
| US-4238407-A | Process for the preparation of nitro diphenyl amine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| EP-0011790-A1 | Process for the preparation of nitrodiphenyl amine derivatives | BAYER AG (DE) | 1980-06-11 | — | — | EP | disclosed |