Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.34 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.34 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.34 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.34 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | CD40 | P25942 | 2/20 | 0.33 |
| ▸ | CD40LG | P29965 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065857 | 0.85 | TTR (0.47) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL9614841 | 0.75 | TTR (0.50) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL7744816 | 0.74 | TTR (0.51) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29360969 | 0.74 | TTR (0.58) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL179823 | 0.74 | TTR (0.58) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL9781032 | 0.74 | TTR (0.35) | TTRFABP4CCNA2CDK2MAPK14 | |
| Water SCHEMBL7765550 | 0.73 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL21240726 | 0.73 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL2984538 | 0.73 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL1742117 | 0.72 | TTR (0.59) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382111-A1 | Copper complex-formazane compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-08-16 | — | — | EP | disclosed |