SCHEMBL10437720

SCHEMBL10437720

O=C(O)Oc1cc2cc(Br)ccc2cc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
POLB P06746 1/20 0.44
MCL1 Q07820 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
NCEH1 Q6PIU2 3/20 0.44
LMNA P02545 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ATM Q13315 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP2A6 P11509 1/20 0.38
ERN1 O75460 1/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
CES2 O00748 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7516254 0.83 KMT2A (0.42) MAPTKDM4EMEN1KMT2ANPC1
SCHEMBL7768952 0.83 MAPT (0.50) MAPTKDM4EMEN1KMT2APOLB
SCHEMBL27499512 0.81 HPGD (0.43) MAPTKDM4EMEN1KMT2APOLB
SCHEMBL2760999 0.80 HPGD (0.46) MAPTKDM4EMEN1KMT2APOLB
SCHEMBL3143555 0.75 CYP2A6 (0.56) MAPTKDM4EMEN1KMT2APOLB
SCHEMBL358356 0.74 GRIN2A (0.50) MAPTKDM4EMEN1KMT2APOLB
SCHEMBL31304861 0.74 GRIN2A (0.50) MAPTKDM4EMEN1KMT2APOLB
SCHEMBL2904410 0.73 POLB (0.38) MAPTKDM4EPOLBLMNAL3MBTL1
SCHEMBL9250304 0.72 KDM4E (0.49) MAPTKDM4EMEN1KMT2APOLB
SCHEMBL9621747 0.72 KMT2A (0.70) MAPTKDM4EMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0362729-A1 Process for producing water insoluble azo dyes on the fibre HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-11 EP disclosed
EP-0312003-A2 Process of manufacturing water insolubles azodyes on the fibre HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-19 EP disclosed
EP-0300390-A1 Trifluoromethyl-alkoxy-anilin, process for their preparation and their use in the ice-colour technique HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-25 EP disclosed