Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 3/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036797 | 0.79 | CDK1 (0.34) | POLA1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL24207973 | 0.79 | KCNH3 (0.41) | POLA1CDK1CDK2TLR8 | |
| SCHEMBL16146635 | 0.77 | XDH (0.42) | CDK1CDK2 | |
| SCHEMBL516302 | 0.75 | ADORA2A (0.39) | CDK1CCNB1 | |
| SCHEMBL16146951 | 0.74 | ADORA2A (0.41) | POLA1CDK1CDK2 | |
| SCHEMBL18546888 | 0.73 | CDK1 (0.34) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL10047120 | 0.73 | L3MBTL1 (0.38) | POLA1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL2306213 | 0.73 | CDK1 (0.32) | POLA1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL4551801 | 0.72 | ADORA2A (0.44) | POLA1CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL23133115 | 0.71 | CDK1 (0.43) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399330-A1 | Modified phosphoramidite process for preparing modified nucleic acids | Roche Diagnostics GmbH (DE) | 1990-11-28 | — | — | EP | disclosed |