SCHEMBL10438486

SCHEMBL10438486

CCCCCCCCCCCCCCC(CCC)NS(=O)(=O)N(Cc1ccccc1)C(=O)C(O)C(O)CO

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.37
CNR2 P34972 2/20 0.37
CERT1 Q9Y5P4 3/20 0.35
MMP1 P03956 1/20 0.35
MMP9 P14780 1/20 0.35
MMP13 P45452 1/20 0.35
ADRB3 P13945 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL963233 0.79 MEN1 (0.44)
SCHEMBL10438489 0.71 EPHX2 (0.41) CNR2
SCHEMBL963552 0.69 MEN1 (0.46)
SCHEMBL28034004 0.65 SMN1; SMN2 (0.62) MMP1MMP9MMP13
SCHEMBL8733329 0.65 MEN1 (0.42) CNR2
SCHEMBL1856691 0.65 CNR2 (0.72) CNR2
SCHEMBL966298 0.65 CA12 (0.50) CNR2
SCHEMBL1852549 0.65 CNR2 (0.72) CNR2
SCHEMBL9775631 0.64 HDAC8 (0.51)
SCHEMBL31616456 0.64 CNR2 (0.70) CNR2CERT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0353474-A2 Glycerin derivative and its pharmacological use Eisai Co., Ltd. (JP) 1990-02-07 EP disclosed