SCHEMBL10438869

SCHEMBL10438869

ClC(Cl)=C(Cl)c1ccccc1.ClC(Cl)=Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 1/20 0.44
FBP1 P09467 1/20 0.41
PRMT1 Q99873 1/20 0.40
ESR1 P03372 1/20 0.39
CYP19A1 P11511 2/20 0.38
CYP11B2 P19099 2/20 0.38
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
POLB P06746 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
HIF1A Q16665 1/20 0.37
TSHR P16473 2/20 0.36
AKR1C3 P42330 1/20 0.36
DAO P14920 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15753875 0.87 ALDH1A1 (0.38) AKR1C1FBP1PRMT1ALDH1A1MAPT
SCHEMBL40189 0.84 FBP1 (0.52) AKR1C1FBP1ESR1ALDH1A1MAPT
SCHEMBL59763 0.82 TSHR (0.50) ESR1ALDH1A1LMNAMAPTPOLB
SCHEMBL10697273 0.76 AKR1C1 (0.41) AKR1C1FBP1PRMT1ESR1CYP19A1
SCHEMBL8974736 0.76 ALDH1A1 (0.42) AKR1C1FBP1PRMT1ESR1ALDH1A1
SCHEMBL6065187 0.73 PLAU (0.50) AKR1C1FBP1PRMT1ESR1CYP19A1
SCHEMBL6065194 0.73 PLAU (0.50) AKR1C1FBP1PRMT1ESR1CYP19A1
SCHEMBL6065195 0.73 PLAU (0.50) AKR1C1FBP1PRMT1ESR1CYP19A1
SCHEMBL5491736 0.72 FBP1 (0.42) FBP1CYP19A1CYP11B2ALDH1A1LMNA
SCHEMBL3940726 0.71 TSHR (0.56) ESR1ALDH1A1LMNAMAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0363198-A2 Positive working photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1990-04-11 EP disclosed
EP-0270709-A1 Process for the production of vinyl polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-06-15 EP disclosed