Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40189 | 0.81 | FBP1 (0.52) | AKR1C1FBP1AKR1C3ESR1ALDH1A1 | |
| SCHEMBL8974736 | 0.81 | ALDH1A1 (0.42) | AKR1C1FBP1AKR1C3PRMT1ESR1 | |
| SCHEMBL297455 | 0.78 | — | — | |
| SCHEMBL11024655 | 0.76 | CES1 (0.41) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| Hydrogen Sulfide SCHEMBL30522462 | 0.76 | CES1 (0.41) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL10438869 | 0.76 | AKR1C1 (0.44) | AKR1C1FBP1AKR1C3PRMT1ESR1 | |
| SCHEMBL4704674 | 0.72 | FBP1 (0.48) | AKR1C1FBP1AKR1C3ESR1ALDH1A1 | |
| SCHEMBL6065194 | 0.70 | PLAU (0.50) | AKR1C1FBP1AKR1C3PRMT1ESR1 | |
| SCHEMBL6065187 | 0.70 | PLAU (0.50) | AKR1C1FBP1AKR1C3PRMT1ESR1 | |
| SCHEMBL6065195 | 0.70 | PLAU (0.50) | AKR1C1FBP1AKR1C3PRMT1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272412-A2 | Aromatic carbonate articles bonded by a photocured acrylic composition | GENERAL ELECTRIC COMPANY (US) | 1988-06-29 | — | — | EP | disclosed |