Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19342748 | 0.82 | KDM4E (0.44) | KMT2APOLBESR1CACNA1HPARP1 | |
| SCHEMBL4363219 | 0.78 | GAA (0.43) | KMT2APOLBESR1PARP1PARP4 | |
| SCHEMBL13908159 | 0.78 | CACNA1H (0.53) | KMT2APOLBESR1HRH4CACNA1H | |
| SCHEMBL10439086 | 0.75 | KMT2A (0.43) | KMT2APOLBPDE10AMEN1PKM | |
| SCHEMBL11749738 | 0.74 | GAA (0.40) | KMT2APOLBESR1PARP1PARP4 | |
| SCHEMBL26260442 | 0.74 | PARP1 (0.43) | KMT2APOLBESR1HRH4PARP1 | |
| SCHEMBL11316545 | 0.71 | PGK1 (0.42) | KMT2APOLBESR1PARP1PARP4 | |
| SCHEMBL4283192 | 0.71 | ESR1 (0.41) | ESR1HRH4PARP1NPC1RAB9A | |
| SCHEMBL10146528 | 0.70 | PARP1 (0.56) | ESR1PARP1SMN1; SMN2 | |
| SCHEMBL5679402 | 0.67 | NUDT1 (0.51) | KMT2APOLBESR1PARP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393574-A2 | Hexitol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |