Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907870 | 0.82 | KMT2A (0.40) | KMT2APOLBADORA1MAPTKDM4E | |
| SCHEMBL4363225 | 0.78 | ADORA1 (0.54) | KMT2APOLBADORA1MAPTKDM4E | |
| SCHEMBL13907878 | 0.78 | CACNA1H (0.38) | KMT2APOLBADORA1MAPTMEN1 | |
| SCHEMBL10439085 | 0.75 | KMT2A (0.46) | KMT2APOLBPKMMEN1PDE10A | |
| SCHEMBL13907881 | 0.74 | NPC1 (0.37) | KMT2APOLBADORA1MAPTMEN1 | |
| SCHEMBL13907874 | 0.73 | CACNA1H (0.37) | KMT2APOLBADORA1MAPTMEN1 | |
| SCHEMBL11749723 | 0.73 | TSHR (0.36) | KMT2APOLBADORA1MAPTKDM4E | |
| SCHEMBL13907876 | 0.72 | IDO1 (0.43) | KMT2APOLBADORA1MAPTMEN1 | |
| SCHEMBL11316555 | 0.71 | PGK1 (0.42) | KMT2AADORA1MAPTMEN1TDP1 | |
| SCHEMBL5850166 | 0.70 | PARP1 (0.43) | KMT2APOLBMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393574-A2 | Hexitol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |