Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.38 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.38 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.38 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.38 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.38 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.38 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.38 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346415 | 0.88 | MAPT (0.42) | MAPTNFKB1THPOHIF1AHSD17B10 | |
| SCHEMBL10556304 | 0.81 | HSD17B1 (0.42) | MAPTNFKB1THPOHIF1AHSD17B10 | |
| SCHEMBL16252317 | 0.80 | OPRK1 (0.57) | DRD2 | |
| SCHEMBL345292 | 0.80 | DRD3 (0.57) | MAPTDRD2 | |
| SCHEMBL345291 | 0.80 | DRD3 (0.57) | MAPTDRD2 | |
| SCHEMBL346833 | 0.80 | OPRK1 (0.57) | DRD2 | |
| SCHEMBL15431061 | 0.78 | FAAH (0.36) | CYP1A2TBXAS1 | |
| SCHEMBL10439103 | 0.76 | CYP1A2 (0.43) | MAPTHSD17B10ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL24440190 | 0.75 | HDAC8 (0.42) | ALDH1A1CYP1A2 | |
| SCHEMBL4621176 | 0.75 | BRD4 (0.44) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399814-A2 | Phenol derivatives for promoting human nerve growth factor | Sankyo Company Limited (JP) | 1990-11-28 | — | — | EP | disclosed |