SCHEMBL10439752

SCHEMBL10439752

Clc1ccc(NNc2ccccc2Cl)c(Cl)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
MAPT P10636 3/20 0.56
TDP1 Q9NUW8 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
LMNA P02545 2/20 0.50
GAA P10253 1/20 0.50
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
HTT P42858 1/20 0.47
KDM4E B2RXH2 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
GRIK1 P39086 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
ALOX12 P18054 1/20 0.43
GPR55 Q9Y2T6 1/20 0.43
EGFR P00533 1/20 0.42
TAS1R3 Q7RTX0 1/20 0.42
TAS1R1 Q7RTX1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31482338 0.83 LMNA (0.53) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL8663534 0.83 LMNA (0.53) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL9082349 0.80 TP53 (0.50) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL21858368 0.79 ALDH1A1 (0.70) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL31206286 0.79 ALDH1A1 (0.70) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL4062316 0.78 FADS1 (0.50) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL6338340 0.77 TSHR (0.48) ALDH1A1MAPTTDP1MEN1KMT2A
SCHEMBL9313409 0.76 MEN1 (0.67) ALDH1A1TDP1MEN1KMT2AL3MBTL1
SCHEMBL257705 0.76 LMNA (0.44) ALDH1A1MAPTTDP1LMNAGAA
SCHEMBL14504209 0.76 TSHR (0.47) ALDH1A1MAPTTDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0350022-A2 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1990-01-10 EP disclosed