Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30886668 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL104257 | 0.82 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11910412 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP1A2ALDH1A1KDM4EMAPK1 | |
| SCHEMBL25863824 | 0.75 | SMN1; SMN2 (0.41) | SMN1; SMN2GAACYP1A2ALDH1A1KDM4E | |
| SCHEMBL1640378 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2GAAALDH1A1KDM4EMEN1 | |
| SCHEMBL10134734 | 0.72 | KDM4E (0.40) | SMN1; SMN2GAACYP1A2ALDH1A1KDM4E | |
| SCHEMBL12872695 | 0.72 | CYP2C9 (0.35) | ALDH1A1KMT2AMAPTHSD17B10 | |
| SCHEMBL12647217 | 0.68 | SMN1; SMN2 (0.52) | SMN1; SMN2GAAALDH1A1KDM4EKMT2A | |
| SCHEMBL19050133 | 0.68 | SMN1; SMN2 (0.78) | SMN1; SMN2GAAALDH1A1KDM4ETSHR | |
| SCHEMBL25305134 | 0.67 | CSNK2A1 (0.41) | SMN1; SMN2CYP1A2ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234945-A1 | AZABICYCLYL-SUBSTITUTED HETEROCYCLES AS FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-07-27 | — | — | US | disclosed |
| US-20120059162-A1 | FUSED IMIDAZOLE DERIVATIVE HAVING TTK INHIBITORY ACTION | ONCOTHERAPY SCIENCE, INC. (JP) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059162-A1 | FUSED IMIDAZOLE DERIVATIVE HAVING TTK INHIBITORY ACTION | NR0B1, GRK7, NR5A2 | SMN1; SMN2 4581/4885GAA 4229/4885CYP1A2 1779/4885 |
| US-20230234945-A1 | AZABICYCLYL-SUBSTITUTED HETEROCYCLES AS FUNGICIDES | CYP1B1, DDT, CYP1A1 | SMN1; SMN2 4535/4885GAA 805/4885CYP1A2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.