Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10440318 | 0.78 | AR (0.45) | ARPOLBALDH1A1HTTKMT2A | |
| SCHEMBL11038098 | 0.72 | AR (0.52) | ARPOLBALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL10935874 | 0.71 | AR (0.45) | ARALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9664391 | 0.71 | AR (0.45) | ARPOLBALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL13879455 | 0.69 | KDM4E (0.56) | ARPOLBALDH1A1HTTKMT2A | |
| SCHEMBL13879486 | 0.69 | ALDH1A1 (0.56) | ARPOLBALDH1A1HTTKMT2A | |
| SCHEMBL10463025 | 0.68 | AR (0.40) | ARPOLBALDH1A1KMT2AKDM4E | |
| SCHEMBL1514017 | 0.68 | AR (0.43) | ARPOLBALDH1A1HTTKMT2A | |
| SCHEMBL9382971 | 0.68 | AR (0.42) | ARALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL1513976 | 0.68 | ALDH1A1 (0.52) | ARPOLBALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363585-A1 | N-aryl nitrogen heterocycles | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |