Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24419010 | 0.85 | TSHR (0.48) | ALDH2F9PLAUALDH1A1TSHR | |
| SCHEMBL22542376 | 0.85 | ALDH2 (0.55) | ALDH2F9PLAUALDH1A1TSHR | |
| SCHEMBL11689564 | 0.85 | TDP1 (0.56) | ALDH1A1TSHRHPGDHSD17B10KDM4E | |
| SCHEMBL22542369 | 0.81 | ALDH2 (0.51) | ALDH2F9PLAUALDH1A1TSHR | |
| SCHEMBL9823852 | 0.79 | GAA (0.47) | ALDH2F9PLAUALDH1A1HPGD | |
| SCHEMBL4017962 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TSHRHPGDHSD17B10KDM4E | |
| SCHEMBL21415510 | 0.78 | HPGD (0.56) | ALDH2F9PLAUALDH1A1TSHR | |
| SCHEMBL20097882 | 0.78 | HPGD (0.56) | ALDH2F9PLAUALDH1A1TSHR | |
| SCHEMBL10051619 | 0.78 | TAS1R3 (0.40) | ALDH1A1TSHRTAS1R3TAS1R1GAA | |
| SCHEMBL11691601 | 0.78 | CASP1 (0.45) | ALDH1A1TSHRKDM4EMAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363585-A1 | N-aryl nitrogen heterocycles | BAYER AG (DE) | 1990-04-18 | — | — | EP | disclosed |