SCHEMBL10440348

SCHEMBL10440348

C=Cc1ccc(CCOC=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
MET P08581 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
TDP1 Q9NUW8 1/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
TSHR P16473 1/20 0.33
LMNA P02545 2/20 0.32
PSMD14 O00487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169595 0.84 ALDH1A1 (0.46) ALDH1A1CA12CA1METCA4
SCHEMBL23731306 0.80 ALDH1A1 (0.46) ALDH1A1CA9TDP1CHRNB2CHRNB4
SCHEMBL2402230 0.79 ALDH1A1 (0.50) ALDH1A1CA12CA1METCA4
SCHEMBL28295808 0.78 AKR1B10 (0.49) ALDH1A1CA12CA1METCA4
SCHEMBL50012 0.76 ALDH1A1 (0.65) ALDH1A1CA1TDP1CHRNB2CHRNB4
SCHEMBL1647493 0.76 ALDH1A1 (0.65) ALDH1A1CA1TDP1CHRNB2CHRNB4
SCHEMBL6237288 0.76 ESR1 (0.52) ALDH1A1CA12CA1METCA4
SCHEMBL11009805 0.76 CYP2A6 (0.45) ALDH1A1CA1CA9TDP1MAOB
SCHEMBL11349144 0.76 CA12 (0.31) CA12CA1METCA4CA6
SCHEMBL12764315 0.76 TAAR1 (0.45) CA12CA1CA4CA9POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0376751-A1 Polymerizable cyclic urea derivatives and polymers having a pendant urea NIPPON PAINT CO., LTD. (JP) 1990-07-04 EP disclosed