SCHEMBL50012

SCHEMBL50012

C=Cc1ccc(CCc2ccc(C=C)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.65
TSHR P16473 1/20 0.48
GFER P55789 1/20 0.41
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HDAC8 Q9BY41 1/20 0.40
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CHRNA4 P43681 1/20 0.35
POLB P06746 1/20 0.35
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
THRB P10828 2/20 0.34
TP53 P04637 2/20 0.33
MAPT P10636 2/20 0.33
CHKA P35790 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1647493 1.00 ALDH1A1 (0.65) ALDH1A1TSHRGFERESR1ESR2
SCHEMBL9806380 0.90 ALDH1A1 (0.59) ALDH1A1TSHRTDP1POLBMAOA
SCHEMBL1140696 0.89 ALDH1A1 (0.58) ALDH1A1TSHRESR1TDP1HDAC8
SCHEMBL177912 0.89 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8POLB
SCHEMBL6280046 0.88 ALDH1A1 (0.50) ALDH1A1TSHRGFERESR1ESR2
SCHEMBL11113339 0.88 ALDH1A1 (0.50) ALDH1A1TSHRTDP1HDAC8POLB
SCHEMBL891516 0.87 ALDH1A1 (0.55) ALDH1A1TSHRGFERESR1ESR2
SCHEMBL594419 0.87 ALDH1A1 (0.55) ALDH1A1TSHRESR1TDP1MAOB
SCHEMBL3797757 0.87 ALDH1A1 (0.55) ALDH1A1TSHRESR1TDP1MAOB
SCHEMBL6278400 0.87 ALDH1A1 (0.55) ALDH1A1TSHRESR1TDP1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 928 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010660-A Method for preparing 1, 2-bis (4-vinyl phenyl) ethane 济南鼎皓医药科技有限公司 2026-05-12 CN claimed
US-20260117047-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM ELITE ELECTRONIC MAT ZHONGSHAN CO LTD (CN) 2026-04-30 US claimed
US-20260109852-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM ELITE ELECTRONIC MATERIAL (KUNSHAN) CO., LTD. (CN) 2026-04-23 US claimed
EP-4717716-A1 POLYMERIZABLE COMPOSITION, ION EXCHANGE RESIN, ION EXCHANGE MEMBRANE, MEMBRANE ELECTRODE ASSEMBLY, AND HYDROGEN PRODUCTION DEVICE TOKUYAMA CORPORATION (JP) 2026-04-01 EP claimed
US-12570784-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-03-10 US claimed
US-20260049097-A1 LOW DIELECTRIC COMPOUND, MANUFACTURING METHOD THEREOF, RESIN COMPOSITION, AND ARTICLE MADE THEREFROM ELITE ELECTRONIC MATERIAL (ZHONGSHAN) CO., LTD. (CN) 2026-02-19 US claimed
US-20260035559-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM ELITE MATERIAL CO LTD (TW) 2026-02-05 US claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
US-12534572-B2 Resin composition and article made therefrom Elite Material Co., Ltd. (TW) 2026-01-27 US claimed
US-20260022232-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM ELITE MATERIAL CO LTD (TW) 2026-01-22 US claimed
US-7803846-B2 Highly durable polymer electrolytic membrane for a fuel cell having a cross-linked structure JAPAN ATOMIC ENERGY AGENCY (JP) 2010-09-28 US claimed
EP-1966290-A2 POROUS MONOLITHIC ORGANIC COPOLYMER FOR BIOPOLYMER CHROMATOGRAPHY Leopold-Franzens-Universität Innsbruck (AT) 2008-09-10 EP claimed
US-20080033069-A1 Processes for producing nano-space controlled polymer ion-exchange membranes JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 2008-02-07 US claimed
US-7276561-B2 Processes for producing nano-space controlled polymer ion-exchange membranes JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 2007-10-02 US claimed
WO-2007073865-A2 POROUS MONOLITHIC ORGANIC COPOLYMER FOR BIOPOLYMER CHROMATOGRAPHY LEOPOLD-FRANZENS-UNIVERSITÄT INNSBRUCK (AT) 2007-07-05 WO claimed
US-20070144971-A1 Monolithic organic copolymer for biopolymer chromatography LEOPOLD-FRANZENS-UNIVERSITAT INNSBRUCK (AT) 2007-06-28 US claimed
US-20070144972-A1 Monolithic Organic Copolymer for Biopolymer Chromatography LEOPOLD-FRANZENS-UNIVERSITAT INNSBRUCK (AT) 2007-06-28 US claimed
US-20060134493-A1 Highly durable polymer electrolytic membrane for a fuel cell having a cross-linked structure JAPAN ATOMIC ENERGY AGENCY (JP) 2006-06-22 US claimed
US-20060105216-A1 Polymer electrolyte membrane having improved oxidation resistance JAPAN ATOMIC ENERGY AGENCY (JP) 2006-05-18 US claimed
US-20050049320-A1 Processes for producing nano-space controlled polymer ion-exchange membranes JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 2005-03-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA ALDH1A1 1404/4885TSHR 2876/4885GFER 4/4885
US-12534572-B2 Resin composition and article made therefrom GJB2, BPTF, PRPF6 ALDH1A1 3980/4885TSHR 3805/4885GFER 2387/4885
US-20260022232-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM P2RY10, P2RY13, P2RY11 ALDH1A1 2601/4885TSHR 3955/4885GFER 1755/4885
US-20260049097-A1 LOW DIELECTRIC COMPOUND, MANUFACTURING METHOD THEREOF, RESIN COMPOSITION, AND ARTICLE MADE THEREFROM GJB2, GJA1, CDH1 ALDH1A1 2303/4885TSHR 3069/4885GFER 2868/4885
US-20260109852-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM MACF1, SMCHD1, SMC2 ALDH1A1 1434/4885TSHR 4629/4885GFER 438/4885
US-12570784-B2 Method for making embedded hydrogel contact lenses CRYAB, CRYZ, CRYAA ALDH1A1 2345/4885TSHR 3379/4885GFER 1527/4885
US-20260117047-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM ITGAM, CDC73, ITGB8 ALDH1A1 1851/4885TSHR 1654/4885GFER 1582/4885
US-20260035559-A1 RESIN COMPOSITION AND ARTICLE MADE THEREFROM PRPF6, CD79B, P2RY1 ALDH1A1 1680/4885TSHR 4087/4885GFER 1716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.