Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.47 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938199 | 0.85 | ALDH1A1 (0.49) | TSHRTHRBTHRACYP1A2MAPT | |
| SCHEMBL10607568 | 0.83 | TSHR (0.39) | TSHRTHRBTHRACYP1A2KDM4E | |
| SCHEMBL8063043 | 0.82 | SMN1; SMN2 (0.41) | TSHRCYP1A2KMT2AMAPTALDH1A1 | |
| SCHEMBL10609226 | 0.82 | TSHR (0.44) | TSHRTHRBCYP1A2HSD17B10ALDH1A1 | |
| SCHEMBL7766330 | 0.81 | TSHR (0.38) | TSHRTHRBTHRAKMT2AMAPT | |
| SCHEMBL5478851 | 0.81 | TSHR (0.58) | TSHRTHRBTHRAKMT2AMAPT | |
| SCHEMBL9656568 | 0.80 | TSHR (0.47) | TSHRTHRBCYP1A2MAPTALDH1A1 | |
| SCHEMBL4789470 | 0.79 | THRB (0.40) | TSHRTHRBTHRACYP1A2KMT2A | |
| SCHEMBL10611018 | 0.79 | TSHR (0.44) | TSHRTHRBCYP1A2HSD17B10ALDH1A1 | |
| SCHEMBL447953 | 0.79 | THRB (0.51) | TSHRTHRBTHRACYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59133211-A | — | — | None | — | — | JP | disclosed |
| EP-0361409-A2 | Flame-retardant liquid photosensitive resin composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-04-04 | — | — | EP | disclosed |
| US-4812032-A | DIBROMOSTYRENE, DIVINYLBENZENE, HALOGEN CONTAINING ACRYLATE OR METHACRYLATE | TORAY INDUSTRIES, INC. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4721377-A | COPOLYMER OF DIBROMOSTYRENE, DI-(OR TRI-) (METH-)ACRYLATE AND MONO (METH-)ACRYLATE | TORAY INDUSTRIES, INC. (JP) | 1988-01-26 | — | — | US | disclosed |
| EP-0134861-B1 | RESIN MATERIAL FOR PLASTIC LENS AND LENS COMPOSED THEREOF | TORAY INDUSTRIES, INC. (JP) | 1987-12-09 | — | — | EP | disclosed |
| EP-0176874-A2 | A highly-refractive plastic lens | TORAY INDUSTRIES, INC. (JP) | 1986-04-09 | — | — | EP | disclosed |
| EP-0134861-A1 | Resin material for plastic lens and lens composed thereof | TORAY INDUSTRIES, INC. (JP) | 1985-03-27 | — | — | EP | disclosed |
| US-4487904-A | Urethanized acrylic resin material for plastic lens and lens composed thereof | TORAY INDUSTRIES, INC. (JP) | 1984-12-11 | — | — | US | disclosed |
| JP-S59133211-A | RESIN FOR USE IN HIGH-REFRACTIVE INDEX PLASTIC LENS | TORAY IND INC | 1984-07-31 | — | — | JP | disclosed |