SCHEMBL4789470

SCHEMBL4789470

C=CC(=O)OC(COc1c(Br)cc(Br)cc1Br)COc1c(Br)cc(Br)cc1Br

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.40
THRA P10827 6/20 0.40
TSHR P16473 3/20 0.37
HSD17B10 Q99714 1/20 0.34
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN11 Q06124 1/20 0.33
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
AKR1B1 P15121 1/20 0.31
GAA P10253 2/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10794515 0.93 THRB (0.35) THRBTHRATSHRHSD17B10MEN1
SCHEMBL372528 0.90 THRB (0.35) THRBTHRAALDH1A1
SCHEMBL8902286 0.90 THRB (0.44) THRBTHRAGAAMAPTHPGD
SCHEMBL4758376 0.87 TSHR (0.32) THRBTHRATSHR
SCHEMBL28965932 0.85 TSHR (0.40) THRBTHRATSHRHSD17B10MEN1
SCHEMBL14173186 0.81 ALDH1A1 (0.47) THRBTHRATSHRHSD17B10PTPN2
SCHEMBL10440396 0.79 TSHR (0.47) THRBTHRATSHRHSD17B10CYP1A2
SCHEMBL4759200 0.77 KDM4E (0.40) THRBMEN1CYP2C19KMT2AALDH1A1
SCHEMBL10606972 0.76 THRA (0.32) THRBTHRA
SCHEMBL5085759 0.75 ALDH1A1 (0.45) THRBHSD17B10KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US claimed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US claimed
EP-4028480-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2022-07-20 EP claimed
CN-114651049-A Photocurable compositions containing high refractive index monomers for 3D printing applications 阿科玛法国公司 2022-06-21 CN claimed
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY 2005-03-03 US claimed
US-12492275-B2 Photo-curable compositions containing high refractive index monomers for use in 3D printing applications ARKEMA FRANCE (FR) 2025-12-09 US disclosed
US-20240052081-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2024-02-15 US disclosed
EP-4028480-A1 PHOTO-CURABLE COMPOSITIONS CONTAINING HIGH REFRACTIVE INDEX MONOMERS FOR USE IN 3D PRINTING APPLICATIONS ARKEMA FRANCE (FR) 2022-07-20 EP disclosed
CN-114651049-A Photocurable compositions containing high refractive index monomers for 3D printing applications 阿科玛法国公司 2022-06-21 CN disclosed
US-20080145545-A1 METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM CITIBANK, N.A., AS COLLATERAL AGENT 2008-06-19 US disclosed
WO-2008073534-A1 METAL OXIDE AND SULFUR-CONTAINING COATING COMPOSITIONS, METHODS OF USE, AND ARTICLES PREPARED THEREFROM GENERAL ELECTRIC COMPANY (US) 2008-06-19 WO disclosed
US-7271283-B2 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-09-18 US disclosed
US-7271283-B2 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-09-18 US disclosed
US-7271283-B2 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2007-09-18 US disclosed
EP-1512704-A1 High refractive index, UV-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY (US) 2005-03-09 EP disclosed
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom GENERAL ELECTRIC COMPANY 2005-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050049376-A1 High refractive index, uv-curable monomers and coating compositions prepared therefrom MACF1, WASF2, THEM6 THRB 4854/4885THRA 4108/4885TSHR 4739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.