Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055281 | 0.70 | LTB4R (0.40) | MAOAMAOBCYP2A6KMT2AMEN1 | |
| SCHEMBL6748897 | 0.70 | — | — | |
| SCHEMBL18995061 | 0.67 | CYP2A6 (0.36) | CYP2A6KMT2AMEN1LMNATDP1 | |
| SCHEMBL6964424 | 0.66 | — | — | |
| SCHEMBL19222446 | 0.66 | CYP2A6 (0.38) | CYP2A6KMT2AMEN1LMNATDP1 | |
| SCHEMBL18386521 | 0.66 | CYP2A6 (0.35) | CYP2A6KMT2AMEN1LMNATDP1 | |
| SCHEMBL31564493 | 0.65 | KDM4E (0.38) | KMT2AMEN1ALDH1A1USP2HSD17B10 | |
| SCHEMBL18546613 | 0.64 | MAOA (0.47) | MAOAMAOBKMT2AMEN1LMNA | |
| SCHEMBL17428932 | 0.64 | CYP2A6 (0.36) | CYP2A6KMT2AMEN1LMNATDP1 | |
| SCHEMBL2187687 | 0.64 | PTGDR2 (0.66) | KMT2AMEN1LMNATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355710-A2 | Phenylalkylthiophenes and related compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-02-28 | — | — | EP | disclosed |