Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110345 | 0.82 | PPARG (0.54) | NPSR1KMT2AMEN1MAOB | |
| SCHEMBL5967441 | 0.81 | CES2 (0.61) | CES2NPSR1SRD5A2KMT2AMEN1 | |
| SCHEMBL5967444 | 0.81 | CES2 (0.61) | CES2NPSR1SRD5A2KMT2AMEN1 | |
| SCHEMBL8020210 | 0.80 | PKM (0.50) | CES2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8020213 | 0.80 | PKM (0.50) | CES2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL6975827 | 0.80 | CES2 (0.44) | CES2NPSR1SRD5A2KMT2AMEN1 | |
| SCHEMBL10441879 | 0.79 | LMNA (0.47) | CES2NPSR1SRD5A2KMT2AMEN1 | |
| SCHEMBL10441785 | 0.79 | LMNA (0.47) | CES2NPSR1SRD5A2KMT2AMEN1 | |
| SCHEMBL9658191 | 0.78 | CA12 (0.52) | ALDH1A1POLBKDM4EMAPTGAA | |
| SCHEMBL6819302 | 0.78 | KMT2A (0.57) | CES2NPSR1SRD5A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386940-A1 | 6-Beta-(alpha-etherified oxymino)-acyl amino penicillins | BEECHAM GROUP PLC (GB) | 1990-09-12 | — | — | EP | disclosed |