Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CFD | P00746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149946 | 0.82 | TSHR (0.49) | CFDTSHRKDM4EALDH1A1GAA | |
| SCHEMBL17086902 | 0.81 | CFD (0.48) | HTTCFDTSHRKDM4EALDH1A1 | |
| SCHEMBL10442007 | 0.81 | MAPK1 (0.45) | MAPK1HTTCFDTSHRKDM4E | |
| SCHEMBL28427140 | 0.78 | NCEH1 (0.50) | HTTCFDTSHRKDM4EALDH1A1 | |
| SCHEMBL12967710 | 0.78 | CFD (0.46) | MAPK1HTTCFDTSHRKDM4E | |
| SCHEMBL10546986 | 0.77 | MAPK1 (0.52) | MAPK1HTTCFDTSHRKDM4E | |
| SCHEMBL9477803 | 0.76 | CFD (0.44) | MAPK1HTTCFDTSHRKDM4E | |
| SCHEMBL286701 | 0.76 | PTPN1 (0.46) | MAPK1HTTCFDTSHRKDM4E | |
| SCHEMBL5212814 | 0.76 | MAPK1 (0.71) | MAPK1HTTTSHRKDM4EALDH1A1 | |
| SCHEMBL7565582 | 0.75 | PTPN1 (0.51) | MAPK1HTTCFDTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360298-A2 | Intermediate compounds for use in the synthesis of cephalosporin derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |