SCHEMBL10442011

SCHEMBL10442011

Cc1ccc(C(=O)NC(C)c2cccs2)s1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.63
ALDH1A1 P00352 3/20 0.53
POLB P06746 2/20 0.53
MAPT P10636 1/20 0.53
HPGD P15428 1/20 0.53
TAS1R3 Q7RTX0 1/20 0.50
TAS1R1 Q7RTX1 1/20 0.50
HDAC3 O15379 3/20 0.47
HDAC4 P56524 3/20 0.47
HDAC1 Q13547 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.46
HDAC6 Q9UBN7 3/20 0.46
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.45
PDE4A P27815 1/20 0.44
PDE4B Q07343 1/20 0.44
PDE4C Q08493 1/20 0.44
PDE4D Q08499 1/20 0.44
HRH2 P25021 1/20 0.43
HRH1 P35367 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6030315 0.83 ALDH1A1 (0.51) GAAALDH1A1POLBMAPTHPGD
SCHEMBL10441736 0.83 HPGD (0.59) ALDH1A1POLBMAPTHPGDHDAC1
SCHEMBL2201077 0.81 HDAC6 (0.67) GAAALDH1A1POLBMAPTHPGD
SCHEMBL27826689 0.78 ALDH1A1 (0.52) GAAALDH1A1POLBMAPTHPGD
SCHEMBL24195863 0.78 HDAC3 (0.75) ALDH1A1POLBHPGDTAS1R3TAS1R1
SCHEMBL10441789 0.77 RAB9A (0.54) GAAALDH1A1POLBMAPTHPGD
SCHEMBL12124251 0.76 TAS1R3 (0.63) GAAALDH1A1POLBMAPTHPGD
SCHEMBL2653231 0.76 ALDH1A1 (0.58) ALDH1A1POLBMAPTHPGDL3MBTL1
SCHEMBL10442018 0.75 ALDH1A1 (0.54) GAAALDH1A1POLBMAPTHPGD
SCHEMBL7723792 0.75 ALDH1A1 (0.52) GAAALDH1A1POLBMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0348505-A1 NOVEL N-(1-THIENYLETHYL)AMINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS EFFECTIVE INGREDIENT DAIKIN INDUSTRIES, LIMITED (JP) 1990-01-03 EP disclosed
CN-1033627-A New-N-[1-(thienyl) ethyl] sulfonamide derivatives and contain the weedicide that this compound is an effective ingredient DAIKIN INUDSTRIES LTD (JP) 1989-07-05 CN disclosed