Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440588 | 0.74 | SMN1; SMN2 (0.43) | GAAALDH1A1 | |
| SCHEMBL10443950 | 0.65 | HCRTR2 (0.48) | FFAR1PPARGPPARDHCRTR2 | |
| SCHEMBL5908693 | 0.65 | PLCG1 (0.47) | PHGDHNPC1RAB9AALDH1A1POLB | |
| SCHEMBL6932753 | 0.65 | KMT2A (0.48) | PHGDHNPC1RAB9AGAAALDH1A1 | |
| SCHEMBL10444288 | 0.65 | HTR1A (0.45) | HTR1AHTR1DHTR2CNPC1RAB9A | |
| SCHEMBL10443342 | 0.65 | FFAR1 (0.44) | FFAR1PPARGPPARD | |
| SCHEMBL25228160 | 0.64 | GAA (0.39) | PHGDHGAAALDH1A1POLBKMT2A | |
| SCHEMBL6932007 | 0.64 | HTT (0.53) | GAAALDH1A1POLBNPSR1KMT2A | |
| SCHEMBL3450703 | 0.63 | HSD11B1 (0.42) | PHGDHNPC1RAB9AGAAALDH1A1 | |
| SCHEMBL34466603 | 0.63 | HSD11B1 (0.42) | PHGDHNPC1RAB9AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350163-A2 | Renin inhibitory peptides | BEECHAM GROUP PLC (GB) | 1990-01-10 | — | — | EP | disclosed |