SCHEMBL1044347

SCHEMBL1044347

CCC1(COCCO)COC1.CCC1(COCCOc2ccc(Br)c(Br)c2Br)COC1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
L3MBTL1 Q9Y468 3/20 0.30
MAPT P10636 2/20 0.30
TDP1 Q9NUW8 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL212683 0.94 L3MBTL1 (0.33) TSHRL3MBTL1MAPTTDP1SMN1; SMN2
SCHEMBL29366880 0.82 TSHR (0.34) TSHR
SCHEMBL215820 0.82 TSHR (0.34) TSHR
SCHEMBL216741 0.82 TDP1 (0.34) TSHRL3MBTL1MAPTTDP1SMN1; SMN2
SCHEMBL2991699 0.76 MEN1 (0.41) TSHRMAPT
SCHEMBL216524 0.76 ALDH1A1 (0.39) TSHRMAPT
Tetraethylene Glycol SCHEMBL464913 0.73 MEN1 (0.41) TSHRMAPT
Triethylene Glycol SCHEMBL464912 0.73 MEN1 (0.41) TSHRMAPT
SCHEMBL16274861 0.72 MEN1 (0.37) TSHRMAPT
Di(Hydroxyethyl)Ether SCHEMBL20676740 0.72 TSHR (0.39) TSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8592550-B2 Process for the preparation of polycarbonates STICHTING DUTCH POLYMER INSTITUTE (NL) 2013-11-26 US disclosed
EP-2268708-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATES Stichting Dutch Polymer Institute (NL) 2011-01-05 EP disclosed
WO-2009130182-A1 PROCESS FOR THE PREPARATION OF POLYCARBONATES STICHTING DUTCH POLYMER INSTITUTE (NL) 2009-10-29 WO disclosed
EP-2112187-A1 Process for the preparation of polycarbonates Stichting Dutch Polymer Institute (NL) 2009-10-28 EP disclosed