Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.47 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10443931 | 0.89 | HDAC1 (0.58) | HDAC1HDAC6ALOX5APGRM2GAA | |
| SCHEMBL10443492 | 0.85 | TNF (0.67) | HDAC1HDAC6GRM2SMN1; SMN2TP53 | |
| SCHEMBL10040276 | 0.83 | ALOX5AP (0.69) | HDAC1HDAC6ALOX5APGAASMN1; SMN2 | |
| SCHEMBL10443451 | 0.81 | RAB9A (0.64) | SMN1; SMN2TP53MAPTLMNATSHR | |
| SCHEMBL8395925 | 0.81 | PPARG (0.69) | HDAC1HDAC6GRM2 | |
| SCHEMBL10040282 | 0.81 | MEN1 (0.67) | HDAC1HDAC6ALOX5APGAATP53 | |
| SCHEMBL10443037 | 0.81 | ALDH1A1 (0.72) | GAASMN1; SMN2TP53MAPTNPSR1 | |
| SCHEMBL10443754 | 0.81 | ALDH1A1 (0.49) | GAASMN1; SMN2TP53NPSR1LMNA | |
| SCHEMBL13187206 | 0.80 | ALOX5AP (0.69) | HDAC1HDAC6ALOX5APTP53NPSR1 | |
| SCHEMBL3970228 | 0.79 | HDAC1 (0.64) | HDAC1HDAC6ALOX5APGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0392317-A2 | Benzimidazoles, drugs containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1990-10-17 | — | — | EP | disclosed |